Research

Research standards and reporting guidelines for observational studies have evolved. This project compared and contrasted the identified standards and reporting guidelines regarding observational studies to determine if they were actionable and consistent. Results were published in the Journal of Clinical Epidemiology. Read more

The second phase of a clinical data research network for the Mid-Atlantic region, which partners with three other Universities and associated health systems. Read more

A pragmatic trial that studies the transition from acute to chronic low back pain and compares two treatments that can be delivered in an outpatient setting. Read more

A clinical data research network for the Mid-Atlantic region, which partners with three other Universities and associated health systems. Read more

Building on the work of a group of stakeholders in rural Pennsylvania, this project will test two promising ways for promoting the health, wellness, and recovery of adults with serious mental illness One way will help patients manage their health and health care through a Web-based portal and peer support and the other through interactions with nurses during clinic visits. Read more

A common methodological challenge for comparative effectiveness research is identifying assessments of health status relevant to key stakeholders (patients and healthcare providers). Such instruments should have excellent psychometric properties; be brief; be easy to read, administer, score, and interpret; and be meaningful in the clinical encounter. The project goal is to identify, test, and evaluate patient-centered outcomes instruments that meet these standards. Read more

This project will compare compliance rates with evidence-based screening protocols for child physical abuse before and after implementation of a trigger system within the Cerner emergency medical record using a parallel group randomized controlled trial. It will also compare the accuracy of screening by patient race, insurance status and hospital-type. Read more

Using observational data as a tool for comparative effectiveness research by identifying the best fit of statistical methods, accounting for non-randomized treatment assignment and associated bias and confounding. Read more

This research study will examine if the On the Move program is better than a standard program at improving walking and promoting independence and if the same benefits can be obtained if the On the Move program is delivered by staff of the senior living facilities instead of an exercise leader. Read more

Building on prior work, this project will compare two ways for patients and prescribers to engage in shared decision making around medication treatment appointments in community mental health clinics: person-centered care and measurement-based care. Read more

The aims of this study are (1) to better understand current practices and barriers to use of therapies in early rehabilitation programs, and (2) to subsequently evaluate early rehabilitation programs vs. usual care in children with acute brain injury in the intensive care unit by randomizing children to these groups and measuring outcomes. Read more

Total knee replacement (TKR) decreases pain in numerous patients, but it does not resolve many of the substantial functional limitations and physical inactivity that existed for a long time prior to the surgery, as the knee worsened. There is not enough information to indicate which type of exercise works best for which patients at a later post-TKR www. This study will compare the effectiveness of three treatment approaches after TKR. Read more

Questions such as who improves with treatment, which treatments are most appropriate for whom, and do patients’ perceptions influence outcomes, are highly relevant to patients and clinicians in making healthcare decisions. However, in most research studies, such questions are not addressed. This project focuses on these questions and will contribute to the understanding of treatment outcome differences based upon patients’ views of themselves and their treatment. Read more